C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/46 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2734487
The present invention provides com-pounds of Formula (I): (Chemical formula should be in-serted here as it appears on abstract in paper form) (I) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and pro-drugs of said compounds, wherein wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compo-sitions comprising such compounds are also provided. The compounds of the invention are effective as in-hibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing dieas-es or disorders such as viral infections and virus-related disorders.
La présente invention concerne des composés de formule (I) : (formule chimique à insérer ici telle quelle apparaît dans labstract papier) (I) et les tautomères, isomères, et esters desdits composés, et les sels, solvats, et promédicaments pharmaceutiquement acceptables desdits composés, chacun parmi R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 et n étant choisi indépendamment et tel que défini dans la description. Linvention concerne également les compositions comprenant de tels composés. Les composés de linvention sont efficaces comme inhibiteurs du VHC, et sont utiles, seuls et conjointement avec dautres agents thérapeutiques, dans le traitement ou la prévention de pathologies liées à un virus.
Ananthan Subramaniam
Arasappan Ashok
Bennett Frank
Clark Jeremy
Fowler Anita T.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
Southern Research Institute
LandOfFree
Ethynyl-substituted pyridine and pyrimidine derivatives and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ethynyl-substituted pyridine and pyrimidine derivatives and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ethynyl-substituted pyridine and pyrimidine derivatives and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2079318