Exo- and diastereo- selective syntheses of himbacine analogs

Details Exo- and diastereo- selective syntheses of himbacine analogs Exo- and diastereo- selective syntheses of himbacine analogs

C - Chemistry, Metallurgy

07

D

C07D 307/92 (2006.01) C07C 69/54 (2006.01) C07C 69/606 (2006.01) C07C 205/44 (2006.01) C07C 205/55 (2006.01) C07C 235/28 (2006.01) C07C 309/08 (2006.01) C07D 235/12 (2006.01) C07D 263/56 (2006.01) C07D 277/64 (2006.01) C07D 405/06 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07F 9/58 (2006.01)

Patent

CA 2594871

The application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center. The chemistry taught herein can be exemplified by the following. (I)

L'invention concerne un procédé de préparation d'analogues de l'himbacine utiles comme antagonistes des récepteurs de la thrombine. Le procédé est fondé partiellement sur l'utilisation d'une épimérisation dynamique à promotion basique d'un centre nitro chiral. La chimie définie dans la description peut être exemplifiée par celui-ci.

Affiliated with

Also associated with

Rating

Exo- and diastereo- selective syntheses of himbacine analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Exo- and diastereo- selective syntheses of himbacine analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Exo- and diastereo- selective syntheses of himbacine analogs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1424762