Expression of human cromosomal interferon-_ in animal cells

C - Chemistry – Metallurgy – 12 – N

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195/1.2, 195/1.3

C12N 15/85 (2006.01) C07K 14/57 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01)

Patent

CA 1302320

ABSTRACT OF THE DISCLOSURE Plasmids are constructed by using a human interferon-.gamma. chromosomal DNA and expression vectors, and are transformed to animal cell cultures. A chromosomal DNA can be transcribed and spliced normally by the animal host cells and natural glycosylated human interferon-.gamma. is produced.

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