C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/02 (2006.01) A01K 67/027 (2006.01) C07K 14/545 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) G01N 33/48 (2006.01)
Patent
CA 2167580
Transgenic non-human animals with a human interleukin-1.beta. gene under control of the murine metallothionein -1 promoter are provided. The transgenic animals and cell cultures derived therefrom may be used to study inflammation and cognitive disorders.
L'invention concerne des animaux transgéniques non humains avec le gène de l'interleukine- beta humaine sous le contrôle du promoteur de la métallothionéine-1 murine. Les animaux transgéniques et les cultures de cellules dérivées de ces derniers peuvent servir à l'étude des inflammations et des troubles cognitivo-comportementaux.
Chen Howard Y.
Hofmann Kathryn J.
Shaw Alan R.
Trumbauer Myrna E.
Van Der Ploeg Leonardus H.t.
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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