Extrusion process for making compositions with poorly...

Details Extrusion process for making compositions with poorly... Extrusion process for making compositions with poorly...

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/155 (2006.01)

Patent

CA 2607624

A process for preparing solid dosage forms that contain poorly compressible therapeutic compound. The process, for example, provides for the inventive use of an extruder, especially a twin screw extruder, to melt granulate a therapeutic compound(s) with a granulation excipient.

L'invention concerne un procédé de préparation de formes posologiques solides qui contiennent un composé thérapeutique peu compressible. Le procédé concerne par exemple l'utilisation d'une extrudeuse, notamment d'une extrudeuse à deux vis, pour granuler à l'état fondu un ou des composé(s) thérapeutique(s) à l'aide d'un excipient de granulation.

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