Factor viia inhibitor

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 235/18 (2006.01) A61K 31/4184 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2569170

The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.

De nouveaux inhibiteurs des facteurs VIIa, IXa, Xa, XIa, plus particulièrement du facteur VIIa, des compositions pharmaceutiques comprenant ces inhibiteurs et des procédés d'utilisation de ces inhibiteurs pour le traitement ou la prévention des troubles thromboemboliques, du cancer ou de la polyarthrite rhumatoïde. Font également l'objet de cette invention des procédés de préparation de ces inhibiteurs.

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