C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/18 (2006.01) C07F 5/02 (2006.01)
Patent
CA 2569163
The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.
L'invention concerne de nouveaux inhibiteurs des facteurs VIIa, IXa, Xa, XIa, en particulier du facteur VIIa, des compositions pharmaceutiques contenant ces inhibiteurs, et des méthodes pour utiliser ces inhibiteurs dans le traitement ou la prévention de troubles thromboemboliques, du cancer ou de la polyarthrite rhumatoïde. La présente invention porte également sur des procédés pour préparer ces inhibiteurs.
Dickman Daniel A.
Kumar Dange Vijay
O'bryan Colin
Rai Roopa
Shrader William Dvorak
Pharmacyclics Inc.
Sim & Mcburney
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