C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/44 (2006.01) A61K 39/018 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2531329
The invention relates to Babesia proteins of a 28kDa protein family and to immunogenic fragments of such proteins, to nucleic acids encoding such proteins or fragments, to cDNA fragments, recombinant DNA molecules, live recombinant carriers, or host cells comprising such nucleic acids, to vaccines, to methods for the preparation of such vaccines, to the use of such proteins or fragments for the prophylactic or therapeutic treatment of an infection or its clinical signs caused by an organism of the family Babesiidae, and to diagnostic tests for detection of nucleic acids, antibodies or antigens of an organism of the family Babesiidae.
L'invention concerne des protéines de Babesia d'une famille de protéines 28kDa ainsi que des fragments immunogènes de telles protéines, des acides nucléiques codant de tels protéines ou fragments, des fragments d'ADNc, des molécules d'ADN recombinantes, des supports recombinants vivants ou des cellules hôtes comprenant de tels acides nucléiques, des vaccins, des procédés de préparation de tels vaccins, l'utilisation de tels protéines ou fragments pour le traitement prophylactique ou thérapeutique d'une infection ou de ses signes cliniques provoqués par un organisme de la famille des Babesiidae, ainsi que des essais diagnostiques pour la détection d'acides nucléiques, d'anticorps ou d'antigènes d'un organisme de la famille des Babesiidae.
Carcy Bernard Piere Dominique
Cibrelus Prisca Laetitia
Depoix Delphine
Gorenflot Andre Francois
Moubri Karina
Akzo Nobel N.v.
Fetherstonhaugh & Co.
Intervet International B.v.
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