Famotidine intermediates and their preparation

Details Famotidine intermediates and their preparation Famotidine intermediates and their preparation

C - Chemistry, Metallurgy

07

C

260/541.1

C07C 307/06 (2006.01) C07C 303/34 (2006.01)

Patent

CA 1313677

ABSTRACT Halogenated N-sulfamyl propionamidine addition salts corresponding to the formula Image are provided, in which X represents halogen and A represents an acid selected from sulfuric acid, nitric acid, benzenesulfonic acid; toluenesulfonic acid; 2,4,5- trichlorobenzenesulfonic acid; trichloroacetic acid; trifluoroacetic acid or methanesulfonic acid, are provided. They are useful as intermediates in the preparation of famotidine. They are prepared by reacting a halogenated proprionitrile with the respective acid.

605045

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