Farnesyl protein transferase inhibitors

Details Farnesyl protein transferase inhibitors Farnesyl protein transferase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/496 (2006.01) A61K 31/541 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2354774

Disclosed are compounds of formula (1.0), wherein R8 represents a cyclic moiety to which is bound an imodazolylalkyl group; R9 represents a carbamate, urea, amide or sulfonamide group; and the remaining substituents are as defined herein. Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.

L'invention concerne des composés de formule (1.0), dans laquelle R<8> désigne un groupe caractéristique cyclique auquel est lié un groupe imodazolylalkyle; R<9> désigne un carbamate, urée, un groupe amide ou sulfonamide; et les substituants sont tels que définis ci-dessus. L'invention concerne aussi une méthode de traitement du cancer et un procédé d'inhibition de la farnésyl protéine transférase utilisant les composés faisant l'objet de cette invention.

Affiliated with

Also associated with

Rating

Farnesyl protein transferase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Farnesyl protein transferase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Farnesyl protein transferase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1713650