Fatty alcohols and fatty acid esters useful for treatment of...

Details Fatty alcohols and fatty acid esters useful for treatment of... Fatty alcohols and fatty acid esters useful for treatment of...

A - Human Necessities

61

K

A61K 31/22 (2006.01) A61K 31/20 (2006.01) A61K 31/225 (2006.01)

Patent

CA 2442953

Immunomodulators selected from: (a) a saturated or cis-unsaturated C10 - C20 fatty alcohol or an ester thereof with a C1 - C6 alkanoic acid; (b) a monoester of a C2 - C8 alkanediol or of Glycerol with a saturated or cis- unsaturated C10 - C20 fatty acid; and (c) a diester of glycerol with a saturated or cis-unsaturated C10- C20 fatty acid, are useful for treatment of inflammation, particularly immunologically-mediated inflammation such as it occurs in autoimmune diseases.

L'invention concerne des immunomodulateurs sélectionnés dans: (a) un alcool gras saturé ou cis insaturé en C¿10? - C¿20? ou un ester de celui-ci avec un acide alcanoïque en C¿1? - C¿6?; (b) un monoester d'un alcanédiol en C¿2? - C¿8? ou de glycérol avec un acide gras saturé ou cis insaturé en C¿10? - C¿20?; et (c) un diester de glycérol avec un acide gras saturé ou cis insaturé en C¿10?- C¿20?, ces immunomodulateurs étant utiles dans le traitement d'inflammation, notamment une inflammation induite de manière immunologique, telle que dans des maladies auto-immunes.

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