Food grade transglutaminase inhibitor and uses thereof

Details Food grade transglutaminase inhibitor and uses thereof Food grade transglutaminase inhibitor and uses thereof

A - Human Necessities

23

J

A23J 1/20 (2006.01) A23C 9/14 (2006.01) A23C 9/142 (2006.01) A23J 3/08 (2006.01) A23L 1/30 (2006.01) A23L 1/305 (2006.01)

Patent

CA 2427193

Transglutaminase inhibitor containing composition obtainable from milk, in particular from a whey fraction obtainable from skimmed milk by forming a curd from the milk, separating the curd from the whey in a centrifugation step followed by subjecting the whey to an ultrafiltration step or, alternatively, by subjecting the skimmed milk to a diafiltration step, a method for the production of a transglutaminase inhibitor and the use of the transglutaminase inhibitor in the production of food or pharmaceutical compositions and to the use in the preparation of a medicament for the treatment of pathologies.

L'invention concerne une composition contenant un inhibiteur de la transglutaminase que l'on peut obtenir à partir du lait, notamment à partir d'une fraction de lactosérum que l'on peut obtenir à partir de lait écrémé. Un caillé est formé à partir du lait, ce caillé est séparé du lactosérum au cours d'une étape de centrifugation, puis le lactosérum subit une étape d'ultrafiltration, ou bien le lait écrémé est soumis à une étape de diafiltration. L'invention concerne également un procédé pour produire un inhibiteur de la transglutaminase, ainsi que l'utilisation dudit inhibiteur pour produire des compositions alimentaires ou pharmaceutiques et pour préparer un médicament destiné à traiter des pathologies.

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