Formulation for respiratory tract administration

Details Formulation for respiratory tract administration Formulation for respiratory tract administration

A - Human Necessities

61

K

A61K 31/13 (2006.01) A61K 9/12 (2006.01) A61K 9/72 (2006.01) A61K 31/136 (2006.01)

Patent

CA 2234847

A dosage form for intranasal and/or inhalation administration of an analgesic having low opioid receptor binding activity to a warm blooded animal, that includes a pharmaceutically effective amount of the analgesic. A preferred analgesic is tramadol, a tramadol and/or a pharmaceutically acceptable salt, metabolite or derivative thereof. Methods of making and using the formulation according to the invention are also provided.

L'invention concerne une forme galénique pour l'administration intranasale et/ou par inhalation à un homéotherme d'un analgésique présentant une faible activité de fixation des récepteurs opioïdes. Cette forme galénique contient une dose pharmaceutiquement efficace de l'analgésique. Un analgésique préféré est le tramadol, un tramadol et/ou son sel, métabolite ou dérivé pharmaceutiquement acceptable. L'invention concerne également des procédés de fabrication et d'utilisation de cette formulation.

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