C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 259/06 (2006.01) A61K 9/48 (2006.01) A61K 31/167 (2006.01)
Patent
CA 2580367
The present invention provides a pharmaceutical composition or crystalline composition with a specific dissolution profile, which comprises suberoylanilide hydroxamic acid or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. The present invention provides a process of producing said crystalline composition or pharmaceutical composition. The present invention also provides compositions with a specific particle size distribution.
La présente invention porte sur une composition pharmaceutique ou composition cristalline ayant un profil de dissolution spécifique et comprenant un acide suberoylanilide hydroxamique ou un sel acceptable d'un point de vue pharmaceutique de celui-ci ou un hydrate de celui-ci comme ingrédient actif. La présente invention porte également sur un procédé de production de cette composition cristalline ou composition pharmaceutique, ainsi que sur des compositions ayant une granulométrie spécifique.
Capodanno Vincent R.
Cohen Benjamin Max
Cote Aaron S.
Dienemann Erik A.
Gallagher Kimberly
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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