Fractionating apparatus having colonies of pillars arranged...

Details Fractionating apparatus having colonies of pillars arranged... Fractionating apparatus having colonies of pillars arranged...

B - Operations, Transporting

01

L

B01L 99/00 (2010.01) B01D 57/00 (2006.01) B01L 3/00 (2006.01) C12N 15/10 (2006.01) G01N 27/447 (2006.01) G01N 30/60 (2006.01) G01N 15/10 (2006.01) G01N 15/14 (2006.01) G01N 30/02 (2006.01) G01N 30/28 (2006.01)

Patent

CA 2396408

A fractionating apparatus is used for fractionating sample into microstructures different in size, and includes a fractionating unit formed with a fractionating passage; the fractionating passage is defined in a groove formed in a substrate of the fractionating unit, and pillar patches (121) are formed in the groove at intervals wider than the gap among the pillar patches (121); while the sample is migrated through the fractionating passage, small-sized DNA molecules (S) are trapped in the pillar patches (121), and large-sized DNA molecules (L) are smoothly migrated through the wide intervals; this results in that the large-sized DNA molecules (L) reaches the end of the fractionating passage faster than the small-sized DNA molecules without clogging.

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