C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/416 (2006.01) A61P 29/00 (2006.01) C07C 209/24 (2006.01) C07D 231/56 (2006.01) C07D 401/14 (2006.01) C07C 211/42 (2006.01)
Patent
CA 2756058
The present invention discloses novel compounds of general formula (I), or a pharmaceutically acceptable salt or prodrug thereof (in which X1 - X5, R5 - R8b, Z1 - Z2 and Ar1 are defined herein), a method for inhibiting the VR1 receptor in mammals using these compounds, a method for controlling pain in mammals, and pharmaceutical compositions including those compounds and a process for making those compounds.
Bayburt Erol K.
Chambournier Gilles
Cink Russell D.
Gomtsyan Arthur
Hsu Margaret
Abbott Laboratories
Torys Llp
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