Fused heterocyclic derivatives and methods of use

Details Fused heterocyclic derivatives and methods of use Fused heterocyclic derivatives and methods of use

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/5025 (2006.01) A61K 31/52 (2006.01) A61P 35/00 (2006.01) C07D 473/34 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2657327

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

L'invention porte sur des composés choisis qui sont efficaces dans la prophylaxie et le traitement de maladies, telles que les maladies médiées par le HGF. L'invention concerne de nouveaux composés, analogues, promédicaments et sels pharmaceutiquement acceptables de ces derniers, des compositions pharmaceutiques et des procédés de prophylaxie et de traitement de maladies et autres pathologies et états associés au cancer et analogues. L'invention se rapporte aussi à des procédés de fabrication desdits composés et à des intermédiaires utilisés selon ces procédés.

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