A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/095 (2006.01) A61K 39/00 (2006.01) A61K 39/02 (2006.01) C07K 1/00 (2006.01) C07K 14/35 (2006.01)
Patent
CA 2386841
The present invention relates to fusion proteins containing at least two Mycobacterium species antigens. In particular, it relates to nucleic acids encoding fusion proteins that include two or more individual M. tuberculosis antigens, which increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection.
La présente invention concerne des protéines hybrides renfermant au moins deux antigènes de l'espèce micobactérie. L'invention concerne en particulier des acides nucléiques codant pour des protéines hybrides, renfermant deux ou plusieurs antigènes de M. tuberculose individuels, augmentant la sensibilité sérologique du sérum d'individus atteints de la tuberculose. L'invention concerne également des méthodes d'utilisation de ces produits dans des diagnostics, des traitement, et dans la prévention de l'infection de la tuberculose.
Dillon Davin C.
Houghton Raymond L.
Lodes Michael J.
Mcneill Patricia D.
Reed Steven
Corixa Corporation
Fetherstonhaugh & Co.
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