Gas driven gene delivery instrument

Details Gas driven gene delivery instrument Gas driven gene delivery instrument

A - Human Necessities

61

M

A61M 5/307 (2006.01) A61K 48/00 (2006.01) C12M 3/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2501743

A cartridge for use in a compressed gas-driven gene delivery instrument comprises a body with an arcuate linear passage formed on the interior thereof and a deposit of carrier particles coated with genetic material deposited in the passage in the cartridge so that the particles can be dislodged by an expanding gas stream passing through the passage, the cartridge being manually manipulable by a user without the user having to touch the carrier particles deposited on the cartridge. The cartridge may be employed in combination with a cartridge holder in the gene delivery instrument. A method of making the cartridge comprises suspending particles coated with genetic material in a suspension liquid, introducing the suspension of particles into a length of tubing, and removing the suspension liquid from the tubing to leave the particles deposited in the tubing.

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