Gene predictors of response to metastatic colorectal...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2643225

The present invention provides for the identification of genes that are expressed in tumors that are responsive to a given therapeutic regime and whose expression correlates with responsiveness to that therapeutic regime. One or more of the genes of the present invention can be used as markers to identify patients that are likely to be successfully treated by a therapeutic regime.

La présente invention concerne l'identification de gènes qui sont exprimés dans des tumeurs qui réagissent à un schéma thérapeutique donné et dont l'expression est corrélée à la faculté de réponse à un schéma thérapeutique. Un ou plusieurs gènes selon la présente invention peuvent être utilisés en tant que marqueurs pour identifier les patients qui sont susceptibles d'être traités avec succès au moyen d'un schéma thérapeutique.

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