C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 31/7105 (2006.01) A61K 31/713 (2006.01) A61K 45/00 (2006.01) C40B 30/00 (2006.01) C40B 30/04 (2006.01) C40B 40/06 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2668691
The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to IBD (e.g. Crohn's Disease) and/or their response to a particular drug or drugs.
L'invention concerne la sélection d'un ensemble de marqueurs de polymorphismes utilisés dans des études d'association sur l'ensemble du génome sur la base de la cartographie de déséquilibre de liaison. Cette invention relève en particulier des domaines de la pharmacogénomique, du diagnostic, du traitement des patients et de l'utilisation d'informations relatives aux haplotypes génétiques pour prédire, chez un individu, le risque de développer une maladie intestinale inflammatoire (IBD) (telle que la maladie de Crohn) et/ou sa réponse à un ou plusieurs médicaments particuliers.
Allard Rene
Belouchi Abdelmajid
Bruat Vanessa
Croteau Pascal
Franke Andre
Genizon Biosciences Inc.
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
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