Genetically engineered endothelial cells and use thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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167/104, 167/327

C12N 5/00 (2006.01) A61K 48/00 (2006.01) C12N 15/867 (2006.01) A61F 2/00 (2006.01) A61F 2/06 (2006.01)

Patent

CA 2005199

ABSTRACT OF THE DISCLOSURE Endothelial cells are genetically engineered with a gene for a heterologous protein which is a therapeutic agent. The endothelial cells may be seeded onto a vascular graft and implanted in the vascular system of a mammal to produce the therapeutic agent in vivo.

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