Glial derived neurotrophic factor as a neuroprotective agent

Details Glial derived neurotrophic factor as a neuroprotective agent Glial derived neurotrophic factor as a neuroprotective agent

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2204911

The present invention is directed to the use of glial-derived neurotrophic factor (GDNF) to inhibit or prevent seizure activity. The methods of the present invention are accomplished by administering GDNF to patients having or potentially having a neurodegenerative disorder such as epilepsy. Pharmaceutical compositions containing a therapeutically effective amount of GDNF in a pharmaceutically acceptable carrier are also provided.

L'invention concerne l'utilisation du facteur neurotrophique dérivé des cellules gliales (GDNF) pour inhiber ou prévenir l'activité d'attaque. Les procédés selon l'invention consistent à administrer ledit GDNF à des patients présentant ou susceptibles de présenter des troubles neurodégénératifs tels que l'épilepsie. Des compositions pharmaceutiques contenant une dose thérapeutiquement efficace de GDNF dans un vecteur pharmaceutiquement acceptable sont également décrites.

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