C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 41/00 (2006.01) A61K 31/573 (2006.01) A61P 5/44 (2006.01) A61P 27/02 (2006.01) C07J 71/00 (2006.01)
Patent
CA 2731513
The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-re-lated macular degeneration and other diseases of retina and macula lutea.
L'invention porte sur des dérivés nitrooxy d'acétonide de fluocinolone, d'acétonide de triamcinolone, de bétaméthasone et de béclométhasone, sur des procédés permettant leur fabrication, sur des compositions pharmaceutiques contenant ces composés et sur des procédés d'utilisation de ces composés et compositions pour le traitement d'un dème maculaire diabétique, d'une rétinopathie diabétique, d'une dégénérescence maculaire, d'une dégénérescence maculaire liée à l'âge, et d'autres maladies de la rétine et de la macula lutea.
Benedini Francesca
Biondi Stefano
Bonfanti Annalisa
Chiroli Valerio
Ongini Ennio
Gowling Lafleur Henderson Llp
Nicox S.a.
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