Granulates containing liposoluble substances and a process...

Details Granulates containing liposoluble substances and a process... Granulates containing liposoluble substances and a process...

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/00 (2006.01) A61K 9/10 (2006.01)

Patent

CA 2452386

A process is described for the preparation of granulates that contain liposoluble and hydrophobic substances, preferably steroidal substances, and that exhibit rapid and excellent water-dispersibility. The process comprises: a) the dispersion of substance (A) in water in the presence of a surfactant (B), b) the incorporation of a water-soluble polyhydroxylated solid excipient (C) in the aqueous dispersion until a granulable pasty mass is obtained and c) the granulation of the mass. The granulates so obtained are suitable for the preparation, at the time of use, of stable and homogeneous aqueous suspensions that are used for nutritional, cosmetic or, preferably, pharmaceutical purposes.

L'invention concerne un procédé destiné à la préparation de granulés contenant des substances liposolubles et hydrophobes, de préférence des substances à base de stéroïdes, et possédant des propriétés de dispersion rapide excellentes dans l'eau. Ce procédé consiste a) à disperser la substance (A) dans l'eau en présence d'un tensio-actif (B), b) à introduire un excipient solide polyhydroxylé hydrosoluble (C) dans la dispersion aqueuse jusqu'à obtention d'une masse pâteuse pouvant être transformée en granulés et c) à procéder à la granulation de la masse. Les granulés ainsi obtenus sont adaptés à la préparation, au moment de leur utilisation, de suspensions aqueuses stables et homogènes utilisées à des fins nutritionnelles, cosmétiques ou, de préférence, pharmaceutiques.

Affiliated with

Also associated with

Rating

Granulates containing liposoluble substances and a process... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Granulates containing liposoluble substances and a process..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Granulates containing liposoluble substances and a process... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1611752