C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A01K 67/027 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/475 (2006.01) C07K 14/495 (2006.01) C12N 9/00 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2359242
Inhibitors of GDF proteins, such as GDF-8 or GDF-11, are disclosed. Also disclosed are methods for identifying and using the inhibitors, for example, to generate transgenic animals and to treat a variety of diseases.
L'invention se rapporte à des inhibiteurs de protéines GDF growth differentiation factor, telles que GDF-8 et GDF-11. Elle se rapporte également à des procédés d'identification et d'utilisation de ces inhibiteurs dans le but, par exemple, de créer des animaux transgéniques et de traiter une variété de maladies.
Brady James L. Jr.
Liang Li-Fang
Ratovitski Tamara
Sinha Debasish
Topouzis Stavros
Borden Ladner Gervais Llp
Metamorphix Inc.
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