H2-m modified transgenic animals

Details H2-m modified transgenic animals H2-m modified transgenic animals

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A01K 67/027 (2006.01) C07K 14/74 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2242400

A transgenic animal with alterations in the H2-Ma gene is prepared by introduction of an altered H2-Ma gene into a host animal. The resulting transgenic animals do not produce functional H2-M molecules.

Cette invention concerne la conception d'un animal transgénique comportant des modifications du gène H2-Ma par introduction d'un gène H2-Ma modifié chez un animal hôte. Les animaux transgéniques obtenus ne produisent pas de molécules fonctionnelles H2-M.

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