Hadhs molecules as modifiers of the p21 pathway and methods...

Details Hadhs molecules as modifiers of the p21 pathway and methods... Hadhs molecules as modifiers of the p21 pathway and methods...

G - Physics

01

N

G01N 33/53 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2453871

Human HADH genes are identified as modulators of the p21 pathway, and thus are therapeutic targets for disorders associated with defective p21 function. Methods for identifying modulators of p21, comprising screening for agents that modulate the activity of HADH are provided.

Selon cette invention, les gènes HADH humains ont été identifiés comme étant des modulateurs de la voie p21 et constituent donc des cibles thérapeutiques pour des troubles associés à une déficience de la fonction p21. Cette invention porte sur des méthodes d'identification de modulateurs de p21 consistant à rechercher les agents responsables de la modulation de l'activité des HADH.

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