Halo substituted benzo`b! thiophenes with pi3k inhibitory...

Details Halo substituted benzo`b! thiophenes with pi3k inhibitory... Halo substituted benzo`b! thiophenes with pi3k inhibitory...

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/41 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2536930

The present invention provides benzo[b]thiophenes of Formula (I), wherein R3, R4, R5, R6, R7, Y, and L have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (I)

L'invention concerne des benzo[b]thiophènes de formule I, dans laquelle R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, Y et L ont une des valeurs qui leur sont attribuées dans les spécifications, leurs sels pharmaceutiquement acceptables utiles pour traiter des maladies et des états pathologiques, y compris des maladies inflammatoires, des maladies cardio-vasculaires et des cancers. L'invention concerne également des compositions pharmaceutiques qui comprennent un ou plusieurs composés de formule I.

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