C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/57 (2006.01) C07K 16/08 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/50 (2006.01)
Patent
CA 2164601
Protease activity associated with herpes simplex virus (HSV)type 2 was identified. The complete nucleotide and amino acid sequence of the protease was determined. The HSV-2 nucleic acid segment encoding the protease substrate ICP35 was also sequenced. Recombinant vectors and host cells for expressing the protease are also described.
On a identifié l'activité de la protéase associée au virus de l'herpès du type 2. On a déterminé la séquence complète d'acides aminés et de nucléotides de la protéase. On a également séquencé le segment d'acide nucléique du virus de l'herpès du type 2 codant le substrat ICP35 de la protéase. Des vecteurs de recombinaison et des cellules hôtes destinés à exprimer la protéase sont égalements décrits.
Kati Warren M.
Katz Leonard
Mcgonigal Thomas P.
Sarthy Aparna V.
Schoen Sharon E.
Abbott Laboratories
Swabey Ogilvy Renault
LandOfFree
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