Heterobicyclic pyrazole derivatives as kinase inhibitors

Details Heterobicyclic pyrazole derivatives as kinase inhibitors Heterobicyclic pyrazole derivatives as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61P 35/00 (2006.01) C07D 307/68 (2006.01) C07D 333/38 (2006.01) C07D 333/42 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2492673

Bicyclo-pyrazoles of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.

L'invention concerne des bicyclo-pyrazoles représentés par la formule (I) définie dans le descriptif, leurs sels pharmaceutiquement acceptables, un procédé de préparation desdits composés et des compositions pharmaceutiques comprenant lesdits composés. Ces composés peuvent être utiles dans le traitement de maladies associées avec une activité déréglée de la protéine kinase, telle que le cancer.

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