C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/335.5
C07D 205/08 (2006.01) C07D 405/04 (2006.01)
Patent
CA 1215715
ABSTRACT The invention relates to novel diastereomers of the Formula I Image (I) and to a process for preparing them. The process com- prises removing the ethylene ketal group from a com- pound of the general Formula III Image (III) wherein R1 stands for a hydrogen atom or an amide protecting group for a phenyl or benzyl group option- ally substituted by one or more methoxy group(s), and reducing the new compound of the general Formula II Image (II) thus obtained wherein R1 has the same meaning as stated above and isolating the product thus obtained and, if desired, separating the pair of diastereomers thus obtained into the components thereof. The new diastereomers of formula (I) are useful as intermediates in the preparation of thienamycin, a well known anti- biotic.
457319
Doleschall Gabor
Fetter Jozsef
Hornyak Gyula
Lempert Karoly
Nyitrai Jozsef
Biogal Gyogyszergyar Rt
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Richter Gedeon Vegyeszeti Gyar Rt
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