Heterocyclic amide compounds as protein kinase inhibitors

Details Heterocyclic amide compounds as protein kinase inhibitors Heterocyclic amide compounds as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/444 (2006.01) A61K 31/497 (2006.01) A61P 43/00 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2693967

The present invention relates to novel heterocyclic amide compounds of Formula I: as disclosed herein or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are compositions comprising said compounds, and methods for using said compoundsfor treating or preventing a proliferative disease, an anti-proliferative disorder, inflammation, arthritis, a neurological or neurodegenerative disease, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease or a fungal disease.

L'invention concerne de nouveaux composés hétérocycliques d'amide représenté par la formule I : telle que décrite ici, ou un sel, un solvat, un ester, un promédicament ou un stéréo-isomère pharmaceutiquement acceptable de ceux-ci. Des compositions comprenant ces composés, et des procédés pour utiliser ces composés pour traiter ou empêcher une maladie proliférative, un trouble de l'antiprolifération, une inflammation, de l'arthrite, une maladie neurologique ou neurodégénérative, une maladie cardiovasculaire, une alopécie, une maladie neuronale, des dommages ischémiques, une maladie virale ou une maladie fongique sont également décrits.

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