Heterocyclic compounds as platelet aggregation inhibitors

Details Heterocyclic compounds as platelet aggregation inhibitors Heterocyclic compounds as platelet aggregation inhibitors

C - Chemistry, Metallurgy

07

K

C07K 5/075 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07D 213/74 (2006.01) C07D 213/81 (2006.01) C07D 215/42 (2006.01) C07D 239/42 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 491/052 (2006.01) C07K 5/093 (2006.01)

Patent

CA 2155307

A compound of the general formula (I): (M1)n-Q-(M2)1-n-L-A wherein: n is 0 or 1; M1 is an amino group; Q is an aromatic heterocyclic group containing a basic nitrogen atom; M2 is an imino group; L is a template group; and A is an acidic group, or an ester or amide derivative thereof, or a sulphonamide group; and pharmaceutically acceptable salts and pro-drugs thereof, for use in the treatment of a disease in which platelet aggregation mediated by the binding of adhesion molecules to GPIIb-IIIa is involved. Novel compounds are also disclosed.

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