Heterocyclic compounds as positive modulators of...

C - Chemistry – Metallurgy – 07 – D

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C07D 231/10 (2006.01) A61K 31/415 (2006.01) A61K 31/4155 (2006.01) A61K 31/4725 (2006.01) A61P 25/00 (2006.01) C07D 249/04 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2686651

The present invention relates to heterocyclic compounds which are positive modulatorsof metabotropic glutamate receptor. The present invention also relates to the use of these compounds for preparing a pharmaceutical composition and to a method of treating a medical disorder, selected from neurological and psychiatric disorders associated with glutamate dysfunction.

La présente invention porte sur des composés hétérocycliques qui sont des modulateurs positifs du récepteur métabotropique du glutamate. La présente invention porte également sur l'utilisation de ces composés pour préparer une composition pharmaceutique et sur un procédé de traitement d'un trouble médical, choisi parmi des troubles neurologiques et psychiatriques associés à un dysfonctionnement du glutamate.

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