Heterocyclic compounds as protein kinases inhibitors

Details Heterocyclic compounds as protein kinases inhibitors Heterocyclic compounds as protein kinases inhibitors

C - Chemistry, Metallurgy

07

D

C07D 403/08 (2006.01)

Patent

CA 2739884

Provided are novel heterocyclic compounds useful as anti-cancer drugs by suppressing protein kinase activities of growth factor receptors such as c-Met,pharmaceutical compositions containing the same, and methods for using the compound. Also, the pharmaceutical composition containing the compound is useful in treating diseases other than cancer, related to signal transduction pathways operated through a receptors of growth factors and antineo-vascularization, for example, c-Met.

La présente invention concerne un nouveau composé hétérocyclique utilisé comme médicament contre le cancer, qui supprime l'activité protéine kinase des récepteurs du facteur de croissance, tels que c-Met. Elle concerne une composition pharmaceutique contenant ce composé et une méthode d'utilisation du composé. La composition pharmaceutique contenant ce composé est également utile dans le traitement de maladies autres que le cancer et associées aux voies de transduction du signal fonctionnant à travers un récepteur du facteur de croissance et l'anti-vascularisation, notamment c-Met.

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