A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/501 (2006.01) A61P 1/16 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07D 237/00 (2006.01) C07D 403/00 (2006.01)
Patent
CA 2580857
Methods of treating an SCD-mediated disease or condition in a mammal, preferebly a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where x, y, G, J, K, L, M, W, R2, R3, R5 , R5a, R6, R6a, R7, R7a, R8 and R8a are difined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
L'invention concerne des méthodes de traitement d'une maladie ou d'un état à médiation assurée par la SCD chez un mammifère, de préférence un humain. Ces méthodes consistent à administrer à un mammifère nécessitant un tel traitement un composé de formule (I) dans laquelle x, y, G, J, K, L, M, W, R2, R3, R5 , R5a, R6, R6a, R7, R7a, R8 et R8a ont la signification indiquée dans la description. L'invention concerne également des compositions pharmaceutiques comprenant lesdits composés.
Chakka Nagasree
Fu Jian-Min
Hou Duanjie
Kamboj Rajender K.
Kodumuru Vishnumurthy
Gowling Lafleur Henderson Llp
Xenon Pharmaceuticals Inc.
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