C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/06 (2006.01) A61K 31/47 (2006.01) A61P 9/10 (2006.01) C07D 215/233 (2006.01)
Patent
CA 2468497
Compounds of the formula (I) are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis.
La présente invention concerne des composés représentés par la formule générale (I). Ces composés, qui sont des inhibiteurs de l'enzyme Lp-PLA¿2?, sont particulièrement indiqués pour des thérapies, plus particulièrement pour le traitement de l'athérosclérose.
Elliott Richard Leonard
Hickey Deirdre Mary Bernadette
Ife Robert John
Leach Colin Andrew
Liddle John
Gowling Lafleur Henderson Llp
Smithkline Beecham P.l.c.
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