Heterocyclic derivatives useful as anticancer agents

Details Heterocyclic derivatives useful as anticancer agents Heterocyclic derivatives useful as anticancer agents

C - Chemistry, Metallurgy

07

D

C07D 333/38 (2006.01) A61K 31/381 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01) A61P 35/00 (2006.01) C07D 231/44 (2006.01) C07D 275/03 (2006.01) C07D 409/12 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2374247

The present invention relates to compounds of formula (1) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein Z, X, X1, R1, R2 and R3 are as de-fined herein as it relates to pharmaceutical compositions contain-ing the above compounds for the treatment of disorders mediated by angiogenesis in mammals by administration of the above com-pounds.

L'invention concerne des composés de la formule (1), ainsi que des sels pharmaceutiquement acceptables, des promédicaments et leurs solvates. Z, X, X<1>, R<1>, R<2> et R<3> sont tel que définis dans le descriptif qui porte sur des compositions pharmaceutiques contenant lesdits composés pour le traitement de troubles induits par l'angiogénèse chez les mammifères par administration desdits composés.

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