C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 225/02 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2665629
This invention provides novel heterocyclic derived matrix metalloprotease inhibitors of the formula (I) and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing matrix metalloproteases. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions.
L'objet de la présente invention propose de nouveaux inhibiteurs hétérocycliques de métalloprotéases matricielles dérivées de formule (I) et des composés pharmaceutiques comprenant ces inhibiteurs, qui sont utiles pour traiter des troubles améliorés par des métalloprotéases matricielles antagonistes. Cette invention propose également des méthodes thérapeutiques et prophylactiques mettant en oeuvre les présentes compositions pharmaceutiques.
Chakravarty Devraj
Fan Xiaodong
Jackson Paul
Karnachi Prabha
Rhodes Kenneth
Janssen Pharmaceutica N.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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