C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/14 (2006.01) A61K 31/506 (2006.01) A61P 29/00 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01)
Patent
CA 2392931
The present invention relates to compounds of formula (I) wherein R2, R3, R6 and A are defined as in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as osteoarthritis, rheumatoid arthritis, colon cancer and Alzheimer's disease, in mammals (preferably humans, dogs, cats and livestock).
La présente invention concerne des composés représentés par la formule (I), dans laquelle R?2¿, R?3¿, R?6¿ et A sont définis dans les spécifications, des compositions pharmaceutiques les contenant et les utilisations médicinales de ces compositions. Les composés de cette invention conviennent pour le traitement ou l'atténuation d'une inflammation et d'autres inflammations associées à des pathologies, telles que l'ostéoarthrite, l'arthrite rhumatoïde, le cancer du colon et la maladie d'Alzeimer chez les mammifères (de préférence chez l'homme, le chien, le chat et le bétail).
Cheng Hengmiao
Li Jin
Lou Minich Martha
Man Sakya Subas
Marie Lundy Kristin
Pfizer Products Inc.
Smart & Biggar
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