C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/70 (2006.01) C07K 14/22 (2006.01) C07K 19/00 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2400570
Alternative approaches to the heterologous expression of the proteins of Neisseria meningitidis and Neisseria gonorrhoeae. These approaches typically affect the level of expression, the ease of purification, the cellular localisation, and/or the immunological properties of the expressed protein.
La présente invention concerne des approches améliorées et de remplacement relatives à l'expression hétérologue des protéines issues de Neisseria meningitidis et de Neisseria gonorrhoeae. Ces approches affectent spécifiquement le niveau d'expression, la facilité de purification, la localisation cellulaire et/ou les propriétés immunologiques de la protéine exprimée.
Arico Maria Beatrice
Comanducci Maurizio
Galeotti Cesira
Giuliani Marzia Monica
Masignani Vega
Borden Ladner Gervais Llp
Chiron Spa
Novartis Vaccines And Diagnostics S.r.l.
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