High affinity human antibodies to human il-4 receptor

Details High affinity human antibodies to human il-4 receptor High affinity human antibodies to human il-4 receptor

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 37/00 (2006.01) C12N 5/12 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2664343

An isolated human antibody or antibody fragment thereof which binds to human interleukin-4 receptor alpha (hlL-4R.alpha.) with an affinity constant (K0) of less than 200 pM, as measured by surface plasmon resonance.

L'invention concerne un anticorps humain isolé ou un fragment de cet anticorps, qui se lie au récepteur alpha humain de l'interleukine-4 (hIL-4R.alpha.) avec une constante d'affinité (K0) inférieure à 200 pM mesurée par résonance de plasmons de surface.

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