Hirullin polypeptides having anticoagulant activity

C - Chemistry – Metallurgy – 12 – N

Patent

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530/9, 167/103.0

C12N 15/15 (2006.01) A61K 38/58 (2006.01) C07K 14/815 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339106

Novel polypeptides, designated hirullins, have a strong antithrombic activity and can therefore be used for the therapy and prophylaxis of thromboses. Said compound are isolated from the leech Hirudinaria manillensis or are produced by conventional peptide synthesis or by recombinant DNA techniques.

602290

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