Hiv-integrase inhibitors, pharmaceutical compositions, and...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61P 31/18 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 471/12 (2006.01) C07D 471/14 (2006.01)

Patent

CA 2500487

Bicyclic hydroxamate compounds represented by the Formula I are described. The bicyclic hydroxamate compounds and compositions containing those compounds may be used to inhibit or modulate an enzyme activity of HIV Integrase and to treat HIV mediated diseases and conditions.

L'invention concerne des composés d'hydroxamate bicycliques représentés par la formule I. Les composés d'hydroxamate bicycliques et les compositions contenant ces composés peuvent être utilisés pour inhiber ou moduler l'activité enzymatique de l'intégrase du VIH, et pour traiter les maladies et les états pathologiques médiés par le VIH.

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