C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 39/395 (2006.01) A61P 19/08 (2006.01) C07K 16/28 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2481074
Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
L'invention concerne des anticorps monoclonaux et des hybridomes les produisant qui agissent avec une ostéoprotégérine ligand (OPGL). L'invention concerne également des méthodes de traitement des troubles ostéopéniques par administration d'une quantité pharmaceutiquement acceptable d'anticorps à OPGL. L'invention concerne également des procédés de détection de la quantité d'OPGL dans un échantillon au moyen d'anticorps à l'OPGL.
Boyle William J.
Elliott Robin L.
Huang Haichun
Martin Francis Hall
Medlock Eugene
Amgen Inc.
Gowling Lafleur Henderson Llp
Medarex Inc.
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