Human growth hormone variants

Details Human growth hormone variants Human growth hormone variants

C - Chemistry, Metallurgy

07

K

C07K 14/61 (2006.01) A61K 38/27 (2006.01) A61K 47/48 (2006.01) A61P 5/06 (2006.01) A61P 35/00 (2006.01) C07K 1/18 (2006.01) C07K 17/08 (2006.01) C12N 15/18 (2006.01)

Patent

CA 2658039

Human growth hormone variants are disclosed having enhanced affinity for the growth hormone receptor. Also disclosed are human growth hormone variants conjugated to one or more chemical groups, such as poly(ethylene glycol), which is believed to prolong the $i(in vivo) half-life of the variants.

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