Human monoclonal antibody to glycoprotein gpiii of varicella...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/08 (2006.01) C12N 5/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2060509

A human monoclonal antibody against glycoprotein gp III of varicella zoster virus (VZV) and a hybridoma which pro- duces the same. This hybridoma is obtained by sensitizing a human lymphocyte with a gp III antigen in the presence of a mitog- en, fusing the sensitized lymphocyte with a mouse myeloma cell, and selecting a cell line which produces a monoclonal antibody which reacts in an ELISA with a cell monolayer plate but substantially not in an ELISA with a cell homogenate plate.

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