C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
530/13, 195/1.14
C12N 15/86 (2006.01) C07K 14/48 (2006.01) C12N 7/00 (2006.01) C12N 15/10 (2006.01) C12N 15/34 (2006.01) C12N 15/66 (2006.01) C12N 15/866 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1341131
A method for the construction of recombinant DNA molecules capable of producing biologically active human nerve growth factor (hNGF) in insect cells is disclosed. Expression of the mature protein is achieved using the baculovirus expression system. The biologically active hNGF so produced is potentially of value in the treatment of patients suffering from Alzheimer's Disease and other neurological disorders.
607007
Baecker Preston A.
Barnett Jim W.
Burtsztyn-Pettegrew Hela
Chan Hardy W.
Nguyen Binh Trong
Dennison Associates
Syntex (u.s.a.) Inc.
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