Humanized antibody derivatives that recognize difucosyl...

Details Humanized antibody derivatives that recognize difucosyl... Humanized antibody derivatives that recognize difucosyl...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 39/395 (2006.01) A61K 39/42 (2006.01) C07K 16/30 (2006.01) C07K 16/34 (2006.01) C07K 16/46 (2006.01) C12N 15/13 (2006.01) G01N 33/569 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2076432

Human/mouse chimeric and humanized monoclonal antibodies recognizing the difucosyl Lewis blood group antigens Y-6 and B-7-2 are disclosed. They can be used in the treatment of cancer of epithelial origin, of small cell lung cancer and of HIV-infections, especially of AIDS.

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